Historical fabrics in Iran, particularly in the city of Khoy, face the simultaneous challenge of preserving physical authenticity while reducing energy consumption. The cold climate, weak thermal envelopes, high air infiltration, and restrictions on intervention increase dependence on fossil-fuel heating and, together with the limited presence of natural elements, reduce thermal comfort. Biophilic architecture can improve environmental performance through the purposeful integration of natural elements; however, its effectiveness in cold-climate historic buildings has rarely been quantitatively evaluated. This study was conducted using a mixed-methods approach as a scenario-based simulation study. The aim was to comparatively evaluate intervention alternatives and provide a decision-making framework rather than to accurately predict actual energy consumption. The research included physical and technical analysis of buildings, energy simulation under five scenarios, user assessment through questionnaires, and scenario ranking using the Analytic Network Process (ANP). The questionnaire reliability was acceptable, with a Cronbach’s alpha of 0.876. In Kabiri House, the S4 scenario reduced annual heating load from 102.5 to 82.0 kWh/m²·year, cooling load from 10.0 to 5.5 kWh/m²·year, and final energy consumption from 120.0 to 95.0 kWh/m²·year, while increasing thermal comfort hours from 67.5% to 82.5%. In Yousefi House, heating load decreased from 140.0 to 118.0 kWh/m²·year, cooling load from 15.0 to 10.0 kWh/m²·year, and final energy consumption from 160.0 to 136.0 kWh/m²·year, while comfort hours increased from 60.0% to 75.0%. The findings indicate that low-intervention biophilic strategies, when compatible with conservation constraints, can provide a practical basis for improving energy performance, enhancing thermal comfort, and supporting decision-making in cold-climate historic houses